Connexin 47 is a protein that belongs to the connexin family, which are involved in the formation of gap junctions between cells. These gap junctions are vital for intercellular communication and the exchange of ions, metabolites, and signaling molecules. Connexin 47 is specifically found in the central nervous system, where it plays a crucial role in the development and function of oligodendrocytes, which are responsible for producing the myelin sheath that surrounds nerve cells. Mutations in the gene encoding connexin 47 have been associated with a rare genetic disorder called Pelizaeus-Merzbacher-like disease, which affects the white matter of the brain and causes neurological symptoms such as developmental delay and movement abnormalities. Research on connexin 47 aims to understand its role in normal myelin formation and function, as well as its potential implications for diseases of the central nervous system.